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    Research and Development

    SPA Express

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    NIH Grants Policy Updates: Stay Alert to Ongoing Changes

    May 2026

    Photo of a sign outside one of the NIH buildings. CC0 1.0 Universal license.

    NIH has issued numerous grants policy changes and clarifications that affect proposal submission, award management, and post‑award compliance. NIH frequently implements changes through NIH Guide Notices, which take effect immediately and supersede language in the NIH Grants Policy Statement until formally incorporated.

    One recent example is the revised NIH Grants Policy Statement, which reflects updated requirements, clarified expectations, and implementation of broader federal policy changes. In addition, NIH has released notices addressing topics such as subaward oversight, continuous submissions, human subjects classifications, application submission policies, and other areas that directly affect investigators and research administrators.

    Because these updates are issued on a rolling basis, it is important that researchers and administrators regularly monitor NIH’s official policy notices. NIH maintains a centralized, up‑to‑date listing of all grants‑related policy changes, organized by fiscal year, on its Notices of NIH Policy Changes webpage. 

    This page is the best single resource for tracking new and updated requirements, including notices related to the Grants Policy Statement, compliance expectations, and administrative flexibilities or restrictions. NIH policy continues to evolve. Regularly reviewing NIH policy notices is one of the most effective ways to stay informed, avoid compliance issues, and ensure proposals and awards are managed in alignment with current NIH requirements.


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