Bret A. Hassel, PhD
Titles
Professor, Microbiology and Immunology
Assistant Director for Training & Education, UMGCCC
Director, Graduate Program in Molecular Microbiology and Immunology
Director, Nathan Schnaper Intern Program in Translational Cancer Research
Financial Sustainability Co-Chair, UMB CURE Scholars Program
School Affiliation
School of Medicine
Specialties
Microbiology and Immunology
Cancer Research
Medical Education and Training
About
Phone: 410-328-2344
Email: bhassel@som.umaryland.edu
Research in my laboratory focuses on the endonuclease RNase-L that functions in host defense from microbial pathogens and as an endogenous constraint on cell proliferation. I and co-workers were the first to clone RNase-L over 20 years ago and subsequent work from my lab has contributed significantly to our current understanding of its biochemical and biological activities. The long-term goal of my work is to determine the mechanisms by which RNase-L mediates innate immune and tumor suppressor functions with the objective of modulating these activities for therapeutic applications. In addition to my research activities as a PI and laboratory mentor, I serve in multiple training, education and outreach capacities as central components of my professional activities. I am Director of the Molecular Microbiology and Immunology graduate program, have taught in nine graduate and medical school courses and was named Teacher of the Year in 2013.
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