Ying He

Ying He, PhD

Assistant Professor, Department of Pharmaceutical Sciences

SCHOOL OF PHARMACY

  • Research interests

    Molecular pharmacology of chronic pain

    Pain in sickle cell disease, cancer

    Mechanisms of opioid addiction

  • Research approaches

    Pharmacology

    molecular biology

    behavioral neuroscience

Lab or individual page: https://faculty.rx.umaryland.edu/yhe/

 

Publications

He Y, Wilkie DJ, Nazari J, Wang R, Messing RO, DeSimone J, Molokie RJ, Wang ZJ. (2016). PKCd-targeted intervention relieves chronic pain in a murine sickle cell disease model. J Clin Invest;126(8):3053-7. PMID: 27348590

He Y, Wang ZJ. (2015) Nociceptor beta II, delta, and epsilon isoforms of PKC differentially mediate paclitaxel-induced spontaneous and evoked pain. J Neurosci; 35(11):4614-25. PMID: 25788678

He Y, Chen Y, Tian X, Yang C, Lu J, Xiao C, DeSimone J, Wilkie DJ, Molokie RE, Wang ZJ. (2016) CaMKIIα underlies spontaneous and evoked pain behaviors in Berkeley sickle cell transgenic mice. Pain; 157(12):2798-2806. PMID: 27842048

Corder G, Doolen S, Donahue RR, Winter MK, Jutras BL, He Y, Hu X, Wieskopf JS, Mogil JS, Storm DR, Wang ZJ, McCarson KE, Taylor BK. (2013) Constitutive μ-opioid receptor activity leads to long-term endogenous analgesia and dependence. Science; 341(6152):1394-9. PMID: 24052307

He Y, Tian X, Hu X, Porreca F, Wang Z. (2012) Negative reinforcement reveals non-evoked ongoing pain in mice with tissue or nerve injury. J Pain; 13(6):598-607. PMID: 22609247