Tanzania Project

Bacterial Infections and Patterns of Resistance at Muhimbili National Hospital in Dar es Salaam, Tanzania

Lead by Dr. Brenna Roth, MD, PhD

Student grantees: Roger Lin (SOM), Joy Musaerenge (SOP), and Saniya Chaudhry (SOP)

Project Summary

Medical and pharmacy students conducted an evaluation of bacterial causes of infection and the resistance of those organisms to commonly used antibiotics at Muhimbili National Hospital (MNH). MNH is a 1500 bed national referral hospital in Dar es Salaam, Tanzania that sees tens of thousands of patients per year. The students began the project with a review of the literature on antimicrobial resistance (AMR) and antimicrobial stewardship projects in sub-Saharan Africa. During the month of June they were in Tanzania and worked with staff in the microbiology laboratory to collect data on all specimens sent to the MNH microbiology laboratory from July 2018 to June 2019 and enter the data into WHONET. They also met with pharmacists at the hospital to determine the antibiotics that are predominantly ordered and available at MNH. We brought all of this information together through weekly discussions about the literature on AMR and antimicrobial stewardship, their experiences and difficulties with collecting data, and the challenges to antimicrobial surveillance and stewardship at MNH specifically and in low resource settings more generally.  The goal of the project was to analyze aggregated microbiological data from the MNH microbiology laboratory to understand the bacterial causes of infections there and the degree of resistance of these bacteria to commonly used antibiotics at MNH.