Ruixin Zhang, Ph.D.


Ruixin Zhang, Ph.D.

Assistant Professor, Department of Center for Integrative Medicine


Research interests

Acupuncture mechanism on pain in animal models including inflammatory pain, bone cancer pain, osteoarthritis pain, and chemotherapy-induced neuropathy models

Social interaction/support on pain-associated affective response

Research approaches

Optogenetic techinique

Electrophysiology in freely-moving rats

Molecular biology

A battery of behavioral tests including thermal, mechanical, open field, body weight-bearing tests and conditioned place avoidance

Lab or individual page


  1. Zhang RX, Lao L, Ren K, Berman BM (2014) Mechanisms of acupuncture-electroacupuncture on persistent pain. Anesthesiology, 120:482-503.
  2. Zhang RX,  Zhang M, Li A, Pan L, Berman BM, Ren K, Lao L (2013) DAMGO in central amygdala alleviates affective dimension of pain in a rat model of inflammatory hyperalgesia. Neuroscience, 252:359-66.
  3. Zhang RX, Ren, K,Dubner R (2013) Osteoarthritis pain mechanisms: Basic studies in animal models. Osteoarthritis and Cartilage, 21, 1308–1315.
  4. Meng X, Zhang Y, Lao L, Saito R, Li A, Bäckman CM, Berman BM, Ren K, Wei PK, Zhang RX (2013) Spinal interleukin-17 promotes thermal hyperalgesia and NMDA NR1 phosphorylation in an inflammatory pain rat model. Pain, 154 (2): 294-305.
  5. Zhang Y, Zhang RX, Zhang M, Shen XY, Li A, Xin J, Ren K, Berman BM, Tan M, Lao L (2012) Electroacupuncture inhibition of hyperalgesia in an inflammatory pain rat model: Involvement of distinct spinal serotonin and noradrenaline receptor subtypes. British Journal of Anaesthesia 109(2):245-252.