Ohannes Melemedjian, PhD


Ohannes Melemedjian, PhD

Assistant Professor, Department of Neural and Pain Sciences


Research interests

We are interested in elucidating the role of bioenergetics and metabolism in chronic pain states.

Research approaches

Cellular, molecular, biochemical, electrophysiological and behavioral approaches are used in our lab.


  1. Ohannes K. Melemedjian, Dipti V. Tillu, Jamie K. Moy, Marina N. Asiedu, Edward K. Mandell, Sourav Ghosh, Gregory Dussor and Theodore J. Price. 2014. Local translation and retrograde axonal transport of CREB regulates IL-6-induced nociceptive plasticity. Molecular Pain, 10:45.
  2. Ohannes K. Melemedjian*, Galo L. Mejia, Talya S. Lepow, Olivia K. Zoph and Theodore J. Price. 2013. Bidirectional regulation of P body formation mediated by eIF4F complex formation in sensory neurons. Neuroscience Letters, 532, 169-174.
  3. Ohannes K. Melemedjian, Hussein N. Yassine, Adia Shy and Theodore J. Price. 2013. Proteomic and functional annotation analysis of injured peripheral nerves reveals ApoE as a protein upregulated by injury that is modulated by metformin treatment. Molecular Pain, 9:14.
  4. Ohannes K. Melemedjian, Dipti V. Tillu, Marina N. Asiedu, Edward K. Mandell, Caleb J. Taylor, Sourav Ghosh and Theodore J. Price. 2013. BDNF regulates PKMzeta at spinal synapses to initiate and maintain a centralized chronic pain state. Molecular Pain, 9:12.
  5. Ohannes K Melemedjian, Arkady Khoutorsky, Robert E Sorge, Jin Yan, Marina N Asiedu, Arely Valdez, Sourav Ghosh, Gregory Dussor, Jeffrey S Mogil, Nahum Sonenberg and Theodore J Price. 2013. mTORC1 inhibition induces allodynia and sensory neuron hyperexcitability via IRS1-dependent feedback activation of ERK. Pain, 154, 1080-1091.