Man-Kyo Chung, DMD, PhD

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Man-Kyo Chung, DMD, PhD

Associate Professor, Department of Pain and Neural Sciences

SCHOOL OF DENTISTRY

Research interests

Ion chanels in nociceptors


 

Transient receptor potential channels


 

Molecular mechanisms of tooth pain


 

Peripheral mechanisms of craniofacial muscle pain

Research approaches

Electrophysiology


cellular physiology


molecular biology


biochemistry


mouse genetics

 

ORCID ID:  mchung

Publications

  1. Chung M.K., Lee J., Joseph J., Saloman J.L., Ro J.Y. : Peripheral Group I metabotropic glutamate receptor activation leads to muscle mechanical hyperalgesia through TRPV1 phosphorylation in the rat. J Pain, 16:67-76, 2015.
  2. Joseph J., Wang S., Lee J. Ro J.Y., Chung M.K.* : Carboxy terminal domain of transient receptor potential vanilloid 1 contains distinct segments differentially involved in capsaicin- and heat-induced desensitization. J Biol Chem, 288:35690-35702, 2013.
  3. Wang S., Joseph J., Ro J.Y. Chung M.K. *: Modality-specific mechanisms of PKC-induced hypersensitivity of TRPV1: S800 is a polymodal sensitization site. Pain 1156:931-941, 2015.
  4. Wang S., Lee J., Ro J.Y., Chung M.K. : Warmth suppresses and desensitizes damage-sensing ion channel TRPA1, Mol Pain, 8:22, 2012.
  5. Chung M.K., Lee J., Duraes G., Ro J.Y.: Lipopolysaccharide-induced pulpitis up-regulates TRPV1 in trigeminal ganglia, J Dent Res, 90: 1103-1107, 2011.