Matthew Frieman, PhD

Titles

Alicia and Yaya Professor of Viral Pathogen Research

Center for Pathogen Research

Department of Microbiology and Immunology

School Affiliation

School of Medicine

Specialties

  • Virology
  • Coronaviruses
  • Therapeutics

About

I am the Alicia and Yaya Professor of Viral Pathogen Research in The Department of Microbiology and Immunology in The University of Maryland School of Medicine. My laboratory focuses on the pathogenesis of Coronaviruses to better understand how they cause disease. For the past 17 years, I have studied the highly pathogenic SARS-CoV-1, MERS-CoV, and SARS-CoV-2 via genetic, molecular, virological, immunological, and cell biological techniques. We focus on identifying viral proteins that control replication and host protein pathways as well as assessing those viral proteins and host proteins in animal model systems. In addition, we have investigated other human respiratory viruses including seasonal coronaviruses, rhinovirus, influenza virus and respiratory syncytial virus. We have used the combination of in vitro (air-liquid-interface, Lung Chip, human immortalized lung cells) and in vivo models (mouse models of SARS-CoV, SARS-CoV-2, MERS-CoV, Influenza virus) to identify host factors that affect multiple viruses and for the development and evaluation of therapeutics for these important respiratory viruses.

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Tagged: The Future of Health Care   Global Health   Research and Innovation  

This information was last updated May 17, 2023.