Local Signals and Macromolecular Architecture in Heart

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Heart Failure


T. B. Rogers
R. J. Bloch
W. J. Lederer

Molecular Genetics
Cell Biology 

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Project 2: Bloch

Stress-activated Protein Kinases
in the Regulation of Local Structure/Function
in the Cardiomyocyte


Williams, M.W., W.G. Resneck, T. Kaysser, J.A. Ursitti, C.S. Birkenmeier, J.E. Barker and R.J. Bloch (2001) Na,K-ATPase in Skeletal Muscle: Two Populations of b-Spectrin Control Localization in the Sarcolemma but not Partitioning Between the Sarcolemma and the Transverse Tubules J. Cell Sci. 114, 751-762.

Ursitti, J.A., L.A. Martin, T. Chaney, C. Zielke, B.E. Alger, and R.J. Bloch (2001) Spectrin Expression and Localization in the Developing Hippocampus of the Rat. Devel. Brain Res. 129, 81-93.

Williams, M.W., and R.J. Bloch (1999) Extensive but Coordinated Reorganization of the Membrane Skeleton in Myofibers of Dystrophic (mdx) Mice. J. Cell Biol. 144,1259-1270.

Zhou, D., J.A. Ursitti and R.J. Bloch (1998) Developmental Expression of Spectrins in Rat Skeletal Muscle. Molec. Biol. Cell 9, 47-61.

Bezakova, G., and R. J. Bloch (1998) The Zinc Finger Domain of the 43K Receptor-Associated Protein, Rapsyn: Role in Acetylcholine Receptor Clustering. Molec. Cell. Neurosci. 11, 274-288.

De Deyne, P., A. O'Neill, W.G. Resneck, G.M. Dmytrenko, D.W. Pumplin and R.J. Bloch (1998) Vitronectin Receptor Associated with Clathrin-Coated Membrane Domains through the Cytoplasmic Sequence of the ß5 Subunit. J. Cell Sci. 111, 2729-2740.

Zhou, D., C.S. Birkenmeier, M. Williams, J.J. Sharp, J.E. Barker and R.J. Bloch (1997) Small, Membrane-bound, Alternatively Spliced Forms of Ankyrin 1 Associated with the Sarcoplasmic Reticulum of Mammalian Skeletal Muscle. J.Cell Biol. 136:621-631.

Porter, G.A., M.G. Scher, W.G. Resneck, N.C. Porter, V. Fowler and R.J. Bloch. (1997) Two Populations of ß-Spectrin in Rat Skeletal Muscle. Cell Motil. Cytoskel. 37, 7-19.

Luther, P.W., S.J. Samuelsson, R.J. Bloch, and D.W. Pumplin (1996) Rotary Replication of the Neuromuscular Junction: Structures Associated with the Cytoplasmic Surface of Postjunctional Sarcolemma. J. Neurocytol. 25:417-427.

Porter, G.A., G.M. Dmytrenko, J.C. Winkelmann, and R.J. Bloch (1992) Dystrophin Colocalizes with ß-Spectrin in Distinct Subsarcolemmal Domains in Mammalian Skeletal Muscle. J. Cell Biol. 117:997-1005.

P. Welling

Y. Wang



Robert Bloch, PhD, Professor
Department of Physiology, University of Maryland School of Medicine, University of Maryland Baltimore.

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Program Project Grant in Heart Failure

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